WebOct 23, 2024 · CHICAGO – Follow-up out to as long as 11 years from treatment confirmed the long-term efficacy and safety of myeloablative autologous stem cell transplantation for patients with severe scleroderma. This extended follow-up comprised 43 survivors from the 75 patients originally randomized in a controlled, 6-year trial. WebJun 16, 2005 · Severe systemic sclerosis (SSc) is a serious autoimmune disorder in which a person's own immune cells attack organs in the body. SSc affects the skin, …
Characterising the autoantibody repertoire in systemic sclerosis ...
WebMar 31, 2024 · Tashkin DP, Elashoff R, Clements PJ, et al. Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med. 2006;354:2655–66. Tashkin DP, Elashoff R, Clements PJ, et al. Effects of 1-year treatment with cyclophosphamide on outcomes at 2 years in scleroderma lung disease. Intravenous cyclophosphamide While the two Scleroderma Lung Studies (SLS I and SLS II) used daily oral administration cyclophosphamide [26,27], we prefer monthly intravenous administration, as noted above. The effectiveness of intravenous cyclophosphamide, used in combination with low dose … See more INTRODUCTION Interstitial lung disease (ILD) is a frequent complication of systemic sclerosis (SSc) that is often progressive and has a poor prognosis [1-7]. SSc-associated ILD consists of various histopathologic … See more A minority of patients with SSc-ILD have the histopathologic pattern of UIP [8], the characteristic pattern associated with idiopathic pulmonary fibrosis (IPF). This pattern is … See more TYPES OF INTERSTITIAL LUNG DISEASE The term interstitial lung disease (ILD) is broadly used to describe a heterogeneous group of disorders that are classified together because of similar clinical, radiographic, … See more INITIATING THERAPY The optimal treatment for systemic sclerosis-associated interstitial lung disease (SSc-ILD) is not known. … See more restaurants near 76th and rawson
Stem Cell Transplant Boosts Survival in Scleroderma
WebOct 15, 2008 · Systemic sclerosis (systemic scleroderma) is a connective tissue disease associated with autoimmunity, vasculopathy, and fibrosis. The annual incidence is … WebMar 18, 2024 · Cyclophosphamide is widely used to treat severe manifestations of numerous autoimmune rheumatic diseases including systemic sclerosis. Based on … WebOct 15, 2008 · Scleroderma mimics are uncommon conditions that are associated with skin induration, but lack Raynaud phenomenon, internal organ involvement, and autoantibodies. Other diseases, such as mixed or... provision project breast cancer