Phorbol 13-acetate
WebPhorbol 12-myristate 13-acetate Synonym (s): Phorbol-12-myristate-13-acetate, 12-O-Tetradecanoylphorbol 13-acetate, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12 … WebEach vial of this cocktail contains phorbol-12-myristate 13-acetate (40.5 µM), ionomycin (669.3 µM), and Brefeldin A (2.5 mg/ml) in DMSO (500X). Storage & Handling Store cocktail at -70°C upon receipt. Protect from light. Avoid repeat freeze/thaw cycles. Application Activ, FC, ICFC - Quality tested Recommended Usage
Phorbol 13-acetate
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WebOct 11, 2011 · Comparison on the anti-inflammatory effect of Cortex Phellodendri Chinensis and Cortex Phellodendri Amurensis in 12-O-tetradecanoyl-phorbol-13-acetate-induced ear edema in mice J Ethnopharmacol . 2011 Oct 11;137(3):1425-30. doi: 10.1016/j.jep.2011.08.014. WebDescription. PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio.
WebPhorbol 12-myristate 13-acetate is also a model agent to study growth factors-, hormones-, and cytokines-mediated regulation of cellular growth and differentiation. Application … WebMay 3, 2013 · Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized THP-1 (human monocytic leukemia cell line) cells, untreated or treated with …
WebJan 17, 2024 · Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a commonly used PKC activator. Properties Articles 1503 Spectrum Names 12-O-tetradecanoylphorbol-13-acetate Biological Activity Chemical & Physical Properties MSDS Safety Information Synthetic Route Previous 1/2 Next Precursor & DownStream Articles 1503 More Articles … WebSep 16, 2011 · The second set of experiments was a model of ROS production based on the oxidant activities of human monocytes activated with phorbol-12-myristate-13-acetate (PMA), that we designed to study the effect of the plant extracts on the cellular ROS production in inflammation-like conditions, using a fluorescence technique with 2′,7 ...
WebPhorbol 12-myristate 13-acetate upregulates cyclooxygenase-2 expression in human pulmonary epithelial cells via Ras, Raf-1, ERK, and NF-kappaB, but not p38 MAPK, pathways. Cell Signal. 17(3):299-310. 3. Fürstenberger G. et al., 1981. Skin tumor promotion by phorbol esters is a two-stage process. PNAS. 78(12):7722-6. TECHNICAL SUPPORT
WebBergamottin reduced phorbol-12-myristate-13-acetate (PMA)-induced activation of MMP-9 and MMP-2 and further inhibited cell invasion and migration. Bergamottin suppressed … free disc personality test handoutWebPhorbol myristate acetate (PMA; phorbol ester) activates protein kinase C, which then activates a wide range of signaling pathways, including ERK via effects on the upstream kinase Raf. ERK then activates a wide range of downstream targets, … blood tests for triglyceridesWebPhorbol 12-myristate 13-acetate Revision Date 25-Dec-2024 Sensitization No information available Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen. Component CAS No IARC NTP ACGIH OSHA Mexico Tetradecanoyl phorbol acetate (TPA) 16561-29-8 Not listed Not listed Not listed Not listed … freedisc pl arsene lupin wszystkie filmyWebPhorbol myristate acetate (PMA; phorbol ester) activates protein kinase C, which then activates a wide range of signaling pathways, including ERK via effects on the upstream … free discovery word search makerWebmyristate 13-acetate is a NF-κB activator. Phorbol 12-myristate 13-acetate induces differentiation in THP-1 cells[3][7]. IC₅₀ & Target PKC 11.7 nM (EC50) NF-κB In Vitro In order to examine the role of PKC in p38MAPK phosphorylation, the cells are stimulated with the PKC activator, PMA (100 freedisc pl fbi internationalWebThe present study demonstrates an increased phosphorylation of B(0,+) on serine moiety after treatment of rat astrocytes with phorbol 12-myristate 13-acetate, a process correlated with an augmented activity of l-leucine transport and an enhanced presence of the transporter at the cell surface. blood tests for ttsWebJun 3, 2024 · How to properly prepare PMA (Phorbol 12-myristate 13-acetate)? Helly, I've currently bought 1 mg of PMA from sigma to treat U937 cell line differentiation, but now, I'm a bit confused with how... free discovery channel on firestick